Webinar: Innovative Methods Advancing Discovery and Characterization of Antibodies
Join us for a two-part webinar: Innovative Methods Advancing Discovery and Characterization of Antibodies
Date: Thursday, April 24, 2025
Time: 8:00 am PT, 11:00 am ET, 17:00 CET
Part I: Multiple Innovative Technologies & Platforms Empower Antibody Discovery
Abstract: The rapid development of the antibody industry depends on the application of new technologies and platforms. This talk introduces Biointron’s many new technologies and platforms, ranging from antibody development, functional assays, to antibody optimization, such as VHH discovery platform, FCMES affinity maturation platform, AbDrop single B-cell sorting platform, etc. The talk also demonstrates Carterra’s remarkable contributions to these platforms, which have greatly improved the efficiency, quality, and throughput. Numerous cases are displayed to share with the audience.
Part II: Discovery and Characterization of Multi-Specific Antibodies: New Capabilities and Workflow
Abstract: Selection of bi- and tri-specific binders often require the screening of large combinatorial sample sets derived from panels of single domain binders. The Carterra LSA platform makes analyzing the binding properties of these molecules straightforward and requires minimal amounts of mAb sample and antigen. The affinity of the binders to the targets can be measured in several assay formats and used to verify the independence and activity of each binding site for hundreds of clones. Along with the binding kinetics and specificity measurements, the LSA enables large scale epitope binning to ensure diverse sets of clones are being carried forward to functional evaluation.
In this webinar, you’ll learn about:
- VHH discovery platforms
- Affinity maturation
- AbDrop single B-cell sorting
- Binding kinetics and specificity
- High-definition epitope binning using HT-SPR
- Screening crude periplasmic extracts
Who Should Attend:
- Antibody Scientists, Antibody Discovery Scientists, Antibody Engineers, Research Scientists (Immunology), Senior Scientists, Antibody Development, Directors of Antibody Engineering
Speakers:
Daniel Bedinger, PhD, Sr. Manager Field Application Science, Carterra
Daniel Bedinger was instrumental in the launch of Carterra’s LSA platform, perfecting technology, applications and methods and now leads the company’s global Application Science team. He has over two decades of experience in the generation and characterization of therapeutic monoclonal antibodies—most notably at Xoma and Abgenix. Daniel earned his Ph.D. from UC Davis in Cellular and Molecular Physiology.
Long Xu, PhD, R&D Director
Dr. Long Xu earned his undergraduate degree from Nanjing University in China and completed his PhD at Boston University in the United States. With over a decade of experience, Dr. Xu worked at Washington University in St. Louis, Lighting Research Center, and other internationally renowned institutions. His research spans multiple disciplines within life sciences and health, including DNA damage and repair, DNA photoreactivation, lighting and health, etc. In 2022, he joined the Biointron team, focusing on the establishment of various high-quality antibody technology platforms, and dedicated to the discovery, optimization, and application research of antibodies.