What the best looks like

Proprietary HT-SPRTM Technology

LSA

  • Market leader in high-throughput antibody characterization
  • Detailed antibody kinetics and epitope binning at the earliest stages of drug discovery
  • Characterization directly from crude material

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LSAXT

  • All the benefits of LSA plus enhanced data quality for more demanding applications
  • Rapid kinetics and weak binders such as FcγRs and cytokine panels
  • Small analyte formats such as peptides, PROTAC®s, and protein inhibitors

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Ultra

  • The most sensitive HT-SPR platform enabling fragment and small molecule interactions
  • Interrogate multiple ligand targets, kinase families, or GPCRs vs a compound library
  • Minute sample consumption with advanced microfluidics and expanded thermal control

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There’s no faster way to discover a therapeutic drug or vaccine.

  • 100x the data
  • 10% of the time to answer
  • 1% of the sample

Eli Lilly developed bamlanivimab, the world’s first COVID-19 therapeutic, on the Carterra LSA platform in a 90-day sprint.

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This is what high throughput kinetics looks like.

You can’t generate this much data any other way.  And if you’re wondering:

  • Screening and characterization in the same step — 384 full kinetic profiles in a day
  • 50x faster — Data quality is the same as your low throughput gold standard instrument
  • 1% of the sample with 185,000 small molecule interactions measured in a week

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This is what a high-res epitope binning looks like.

If you’re not binning or just binning 10s of antibodies at a time, you’re not finding out much about your epitope.

  • Bin up to 384 × 384 antibodies (Auto analysis of 150,000 sensorgrams)
  • Discover the Mechanism of Action quickly and reduce failures in development and the clinic
  • Obtain Intellectual Property rights and lock down features that differentiate your antibody from your competitors

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Want to Learn More?

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News & Events

Vanderbilt University School of Medicine Basic Sciences Adds Carterra’s LSA<sup>XT</sup> Instrument to Speed Drug and Vaccine Research and Advance Patient Care

News

09.25.24

Vanderbilt University School of Medicine Basic Sciences Adds Carterra’s LSAXT Instrument to Speed Drug and Vaccine Research and Advance Patient Care

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Webinars

Free Webinar: Discovery, Characterization, and Generative Deep Learning-Based Humanization of Therapeutic Antibody Candidates

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Publications

A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability

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