HT-SPR Technology
With Options
Our Surface Plasmon Resonance (SPR) platforms can transform your label-free characterization workflow allowing screening and characterization for both large and small molecules in a single step.
“The resulting speed at which this drug discovery and development effort proceeded, with progression to human treatment only 90 days after the initiation of antibody screening, was due to advanced discovery and characterization platforms….”
Eli Lilly
Science Translational Medicine
| Maximum Analyte Throughput | Maximum Ligand Throughput | |||
|---|---|---|---|---|
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| Crude/purified antibody kinetics | ✓ | ✓ | ✓ | ✓ |
| Crude/purified epitope binning | ✓ | ✓ | ✓ | ✓ |
| Peptide/mutant mapping | ✓ | ✓ | ✓ | ✓ |
| Blockade | ✓ | ✓ | ✓ | ✓ |
| Polyspecifity | ✓ | ✓ | ✓ | ✓ |
| Quantitation | ✓ | ✓ | ✓ | ✓ |
| Peptide analytes | ✓ | ✓ | ✓ | |
| Fc Receptor Affinity | ✓ | ✓ | ✓ | |
| DEL compounds | ✓ | ✓ | ✓ | |
| PROTAC®s/molecular glues | ✓ | ✓ | ✓ | |
| Kinase | ✓ | ✓ | ✓ | |
| Membrane proteins | ✓ | ✓ | ✓ | |
| Ligandability | ✓ | ✓ | ||
| Thermodynamics | ✓ | ✓ | ||
| Small molecules (mM to subnanomolar) | ✓ | ✓ | ||
| Fragment Screening | ✓ | |||
| Learn More | Learn More | Learn More | Learn More | |
Instrument Highlights
| Analyte Channels | Ligand Array Spots | Applications | Optional Robot | |
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| Vega True “many-on-few” 48-channels of parallel measurement |
48 | 2 per channel | Small Molecule Large Molecule Screening |
✓ |
| Ultra Most versatile “many-on-one” platform for small molecule and biological discovery |
1 | 192 | Small Molecule Large Molecule |
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| LSAXT Enhanced data quality for antibody discovery |
1 | 384 | Small Molecule (limited) Large Molecule Screening |
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| LSA Detailed antibody kinetic and epitopebinning |
1 | 384 | Large Molecule Screening |
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Sensor Chips & Solutions
Choose from ready-to-use and customizable chip chemistries
The right sensor chip is key to getting optimal assay performance. Fortunately, Carterra offers a broad range of chemistries to handle almost any assay imaginable.
- Options include low, medium, and high capacities as well as distinct chemistries depending on the application.
- Premade surfaces simplify assay setup and design for many standard applications further increasing ease of use.
- Alternatively, customizable surfaces allow the attachment of unique molecules
Kinetics Software
Rapidly analyze 1152 kinetic interactions simultaneously.
- Carterra’s Kinetics software easily performs kinetic and steady state affinity analysis on thousands of interactions.
- Automatic data flagging focuses attention on complex data requiring more investigation.
- Advanced analysis features allow seamless display of trends and replicates.
Epitope Software
Explore epitope diversity at an unprecedented level.
Carterra’s Epitope software takes epitope analysis to a whole new level.
- With the ability to compare up to 150,000 interactions from a single experiment, there’s no excuse for not going big when it comes to epitope characterization.
- Cutting edge network plots distill complex data sets into intuitive epitope relationships.
AI, ML & In Silico Tools
Delivering the scale of data needed to develop and validate AI/ML models
Carterra products are the standard for modern drug discovery processes leveraging AI/ML. The scale of data generated enables a robust design and test strategy to build confidence in models.