Linear polycarboxylate
Name Description Application
HC30M
#4279
Polycarboxylate hydrogel, medium charge density, 30nm coating thickness Moderate ligand capacity for general use
HC200M
#4287
Polycarboxylate hydrogel, medium charge density, 200nm coating thickness Higher ligand capacity for general use

Carboxymethylated dextran
Name Description Application
CMDP
#4282
2D planar carboxymethyldextran surface, <5nm coating thickness Lower ligand capacity for high resolution analysis
CMD50M
#4281
Carboxymethyldextran hydrogel, medium charge density, 50nm coating thickness Moderate ligand capacity for general use
CMD200M
#4280
Carboxymethyldextran hydrogel, medium charge density, 200nm coating thickness Higher ligand capacity for increased levels of immobilization
CMD500M
#4296
Carboxymethyldextran hydrogel, medium charge density, 500nm coating thickness Higher ligand capacity for maximum levels of immobilization

NiNTA
Name Description Application
NiHC200M
#4299
Poly – NTA derivatized linear polycarboxylate hydrogel, medium charge density, 200nm coating thickness High capacity for His-tagged ligand captures

Streptavidin
Name Description Application
SAP
#4295
Streptavidin immobilized on 2D planar carboxymethyl dextran surface, <5nm coating thickness Very low capacity for arraying of biotinylated ligands
SAHC30M
#4294
Streptavidin, immobilized in polycarboxylate hydrogel, medium charge density,
30nm coating thickness

Lower capacity for biotinylated ligand kinetic lawns

SAD200M
#4283

Streptavidin, immobilized in a carboxymethyldextran hydrogel, medium charge density, 200nm coating thickness

High capacity for biotinylated ligand captures


Protein A
Name Description Application
PAHC200M
#4291
Protein A derivatized linear polycarboxylate hydrogel, medium charge density, 200nm coating thickness

High capacity for quantitation of human IgG


Protein A/G
Name Description Application
PAGHC30M
#4292
Protein A/G derivatized linear polycarboxylate hydrogel, medium charge density, 30nm coating thickness

Moderate capacity for kinetics of multi-species IgG

PAGHC200M
#4293
Protein A/G derivatized linear polycarboxylate hydrogel, medium charge density, 200nm coating thickness High capacity for quantitation of multi-species IgG

 

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Notes

While CMD is a well described chemistry for use in biosensors, the linear polycarboxylate chemistry of HC chips provides an alternate surface chemistry to that of CMD in instances of non-specific binding or when differential diffusion characteristics are warranted.

CMD and HC sensor chips can be used to build custom capture surfaces such as anti-mouse or Protein A/G via amine coupling of capture molecules.

When stored at -20 °C CMD and HC surfaces are good for 4 years after purchase, while protein derivatized coatings such as SAD should be used within 2 years.

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