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Accelerated High-Throughput and High-Content Antibody Discovery Targeting SARS-CoV-2 Spike Protein

https://carterra-bio.com/resources/accelerated-high-throughput-and-high-content-antibody-discovery-targeting-sars-cov-2-spike-protein/

https://www.youtube.com/watch?v=EJ58QP7m8B4 Posted by Noah T. Ditto Rapid deployment of antibody discovery technologies capable of high-throughput and high-resolution screening is imperative for the timely development of therapeutics for global pandemics. Risk…

Drug Discovery Chemistry 2025 – San Diego

https://carterra-bio.com/events/drug-discovery-chemistry-2025-san-diego/

DDW Article on Analytical Biophysical Tools To Accelerate Discovery of Therapeutic Antibodies

https://carterra-bio.com/news/ddw-article-on-analytical-biophysical-tools-to-accelerate-discovery-of-therapeutic-antibodies/

BioTechniques Article on Accelerating Biotherapeutic Discovery with High Throughput SPR

https://carterra-bio.com/news/biotechniques-article-on-accelerating-biotherapeutic-discovery-with-high-throughput-spr/

Antibody Responses to Crucial Functional Epitopes as a Novel Approach to Assess Immunogenicity of Vaccine Adjuvants – June 27, 2019

https://carterra-bio.com/resources/antibody-responses-to-crucial-functional-epitopes-as-a-novel-approach-to-assess-immunogenicity-of-vaccine-adjuvants/

…Abstract We are interested in developing a vaccine that prevents genital herpes. Adjuvants have a major impact on vaccine immunogenicity. We compared two adjuvants, an experimental Merck Sharp & Dohme…

A Targeted Boost-and-sort Immunization Strategy Using Escherichia Coli BamA Identifies Rare Growth Inhibitory Antibodies – May 8, 2018

https://carterra-bio.com/resources/a-targeted-boost-and-sort-immunization-strategy-using-escherichia-coli-bama-identifies-rare-growth-inhibitory-antibodies/

Sci Rep. 2018 May 8;8(1):7136. doi: 10.1038/s41598-018-25609-z Rajesh Vij, Zhonghua Lin, Nancy Chiang, Jean-Michel Vernes, Kelly M. Storek, Summer Park, Joyce Chan, Y. Gloria Meng, Laetitia Comps-Agrar, Peng Luan, Sophia…

Massive Antibody Discovery Used to Probe Structure–function Relationships of the Essential Outer Membrane Protein LptD – June 25, 2019

https://carterra-bio.com/resources/massive-antibody-discovery-used-to-probe-structure-function-relationships-of-the-essential-outer-membrane-protein-lptd/

…H, Dalmas O, Shriver S, Tam C, Schneider K, Seshasayee D, Nakamura G, Smith PA, Payandeh J, Koerber JT, Comps-Agrar L, Rutherford ST Abstract Outer membrane proteins (OMPs) in Gram-negative…

Nature: CD229 CAR T Cells Eliminate Multiple Myeloma and Tumor Propagating Cells Without Fratricide

https://carterra-bio.com/resources/cd229-car-t-cells-eliminate-multiple-myeloma-and-tumor-propagating-cells-without-fratricide/

Nat Commun. 2020 Feb 7;11(1):798. doi: 10.1038/s41467-020-14619-z Radhakrishnan SV, Luetkens T, Scherer SD, Davis P, Vander Mause ER, Olson ML, Yousef S, Panse J, Abdiche Y, Li KD, Miles RR,…

Using High Throughput SPR to Assess the Binding Kinetics, Affinities, and Epitope Coverage of Antibody Libraries

https://carterra-bio.com/resources/using-high-throughput-spr-to-assess-the-binding-kinetics-affinities-and-epitope-coverage-of-antibody-libraries/

Summary: The generation of antibodies to source the discovery of therapeutics is highly commoditized and there is a trend towards producing fully human antibodies by in vitro and in vivo…

Antibody Discovery & Other Therapeutic Formats

https://carterra-bio.com/applications/antibody-discovery/

Antibody & Other Therapeutic Formats…