Epitope Mapping of Peptide Libraries Using High Throughput SPR

Summary:

Knowing the precise binding region, or epitope, targeted by a monoclonal antibody (mAb) on its specific target is of great interest for the discovery of therapeutic antibodies, enabling the identification of unique epitopes with biologically-relevant mechanism of action and building one’s intellectual property portfolio. It is also tremendously useful in understanding host responses to pathogens in guiding the design of vaccines.

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