Introduction

High-throughput surface plasmon resonance (HT-SPR) has transformed how real-time, label-free binding is deployed in modern, sophisticated drug discovery processes. These transformations have come from both substantial gains in throughput and reduced sample amounts. Described here is an expansion to the breadth of assays and applications HT-SPR can address by improvements in sensitivity and overall data quality, embodied in the new Carterra LSAXT. With these improvements, the versatility of HT-SPR can now be more easily leveraged in more challenging assay types such as PROTAC®s and kinase inhibitors.

Posted by Noah T. Ditto

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