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…example, a 10 x 10 set of antibodies requires 100 unique tests to complete a bi-directional competition map, whereas a 96 x 96 set would require nearly 10,000 individual analyses….
…biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing one…
…of our methods. The LSA instrument was also used to perform epitope binning and ligand competition studies which revealed over ten unique competitive binding profiles within this group of mAbs….
Benefits of HT-SPR when working with Transmembrane Proteins (TMs) TMs in solution avoid complications with immobilizing on the sensor surface Multiple formats can be used depending on application Detailed kinetics…
…out-of-network allowed amounts between health plans and healthcare providers. The machine readable files are formatted to allow researchers, regulators, and application developers to more easily access and analyze data. https://www.cigna.com/legal/compliance/machine-readable-files…
…is changing the way biologics are discovered,” says Tim Germann, Carterra’s Chief Commercial Officer. “We’re thrilled to invite European drug developers and the research community at large to experience in…
…endeavor exacerbated by difficulties in producing recombinant ion channel proteins in amounts that support drug discovery programs. We have developed a general strategy to address this challenge by combining high-level…
…therapeutic antibody candidates in mouse B cell repertoires. In this study, we compare a deep sequencing and scFv display method that retains native heavy and light chain pairing with a…
ScienceDirect. 2014 Aug 01; doi: 10.1016/j.drudis.2014.05.011 B. Brooks, A. Miles, Y. Abdiche Wasatch Microfluidics, LLC, 825 North 300 West, Suite C325 Salt Lake City, UT 84103, USA. ben@brooks.nu. Rinat Laboratories,…