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…combat these diseases. One such obstacle is throughput, as researchers try to screen and characterize large libraries of antibody candidates as quickly as possible during the early screening process for…
…measured on the LSAXT as compared to the Biacore 8K. Figure 2. Significant reduction in resources required to perform FcγR characterization on the LSAXT as compared with the Biacore 8K….
…action (MOA) when competition is observed. A screening approach that can more readily distinguish orthosteric competition from indirect (allosteric) competition presents key opportunities towards detecting therapeutically unique mAbs. Additionally, identifying…
…chain third complementarity-determining region (CDR H3), a critical specificity determinant. Whether these V germline segment-restricted responses reflect a general epitope specificity restriction of antibodies with shared VH/VL pairing is not…
In the fourth edition of our information-packed Scientist-to-Scientist Series, Alyssa Hughes, Applications Scientist at Carterra, talks to Mike Brown, Senior Scientist at Adimab. https://www.youtube.com/watch?v=9iAqJGLNYfs Posted by Alyssa Hughes View Transcript…
…give researchers the most comprehensive insight into serum immune reactivity, specificity, and epitope binding. “The pandemic has forced the scientific community to find ways to discover and develop therapeutics and…
…quite nicely. So upon a certain combination of receptors being ligated on the NK cell, and missing inhibitory signals, this NK cell packed with granules of these perforins and granzymes…
…times faster than existing platforms, compressing months of work into days and addressing a significant bottleneck in drug discovery. Under Josh’s leadership, the Company recently raised $10M from Telegraph Hill…
Therapeutic Areas in Drug Discovery & Clinical Research…
HT-SPR technology with options Our platforms can transform your label-free characterization workflow allowing screening and characterization, for both large and small molecules, in a single step. Check them out! LSA…