Part 1: Identification of Monoclonal Antibodies that Block Ion Channel Activity

Learn how Tetragenetics has developed a strategy to generate and identify monoclonal antibodies targeting ion channels based on high-level expression of recombinant channels in Tetrahymena thermophila, enabling the development of potent immunogens and tools that allow deep mining of the immune repertoire.

Part 2: Carterra’s High Throughput mAb Discovery and Characterization Platform

Carterra’s LSA can analyze up to 384 binding interactions simultaneously, providing mAb characterization throughput to match the output of the current generation of mAb expression platforms; all antibodies can be rapidly and comprehensively screened so that unique epitopes and potential novel therapeutic candidates are not missed while expanding IP coverage.

Combined with application-focused analytical software, the LSA facilitates high throughput:

  • Kinetic screening
  • Epitope binning
  • Epitope mapping
  • Quantitation

Paul Colussi, PhD
Vice President, Research

Yasmina Noubia Abdiche, PhD
Chief Scientific Officer