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Fully Integrated High Throughput Antibody Screening and Characterization Platform
Perform large competition assays such as epitope binning of 384×384 mAbs in 10% of the time using 1% of the sample requirements of other systems.
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Highest Throughput Epitope Binning Available
Maximize epitope diversity, identify unique epitopes and build your IP portfolio.
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High Throughput Kinetics: Rapidly Screen up to 1152 Samples in a Single Assay
No compromise throughput and data quality with powerful batch-mode processing that enables rapid data analysis of large data sets.
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Visit us at Booth #207 at the Discovery on Target conference in Boston, MA.
Learn how to accelerate the discovery of therapeutic antibodies at our poster presentation.
High Throughput Kinetics
The LSA changes the paradigm, delivering flow-based kinetics for coupled (up to 384 in parallel) and capture (up to 1152 in a single run) formats, enabling rapid screening of mAb libraries for affinity, association and dissociation constants.
Epitope Binning
Characterize and group (bin) up to 384×384 mAbs by the epitope binding regions generated against a specific antigen using the LSA’s simple to use classical and pre-mix methods to maintain epitope diversity and provide important information to broaden intellectual property protection.
Quantitation
Rapidly determine the mAb concentration of up to 1152 clones in parallel to aid in production QC and subsequent screening and selection using the LSA Quant App.
Epitope Mapping
Antibody epitope discovery at the amino acid level by immobilizing a panel of up to 384 biotinylated peptides with overlapping sequences and screening mAbs to ‘map’ and compare their binding.
News & Events
Event
09.17.19 through 09.19.19Discovery on Target
Visit us at Booth #207 at Discovery on Target in Boston, MA.
News
05.15.19GEN Article: A Therapeutic Antibody Characterization Trinity Accelerates Drug Development
The three core applications of high throughput SPR that form the antibody characterization trinity are capture kinetics, epitope binning, and epitope mapping. Together, they provide a comprehensive characterization of antibody libraries with minimal sample consumption, enabling more confident decisions to be made earlier and obviating the need for preliminary ELISA screening.
