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…thousands of samples in a week using ultra-low sample quantities Emerging Diseases Require New Tools Medicines to treat and prevent infectious diseases cover a broad range of modalities from dosed…
…through study Day 6 following viral inoculation. This antibody has entered clinical testing and is being evaluated across a spectrum of COVID-19 indications, including prevention and treatment. Introduction The global…
…properties and neutralization activities comparable to the best from hyperimmune sources. This demonstrates that appropriately designed and constructed naïve antibody libraries can effectively compete with immunization to directly provide therapeutic…
Benefits of HT-SPR when working with Transmembrane Proteins (TMs) TMs in solution avoid complications with immobilizing on the sensor surface Multiple formats can be used depending on application Detailed kinetics…
…example, a 10 x 10 set of antibodies requires 100 unique tests to complete a bi-directional competition map, whereas a 96 x 96 set would require nearly 10,000 individual analyses….
Frequently Asked Questions…
…Roberto Arriga, Silvia Maria Serrao, Valentina Peluzzi, Eugenia Principato, Mirco Compagnone, Eleonora Pinto, Laura Luberto, Daniela Stoppoloni, Armin Lahm, Rüdiger Groß, Alina Seidel, Lukas Wettstein, Jan Münch, Andrew Goodhead, Judicael…
…COVID-19. This new high throughput method can be applied for the assessment of the quality of the immune reaction of healthy individuals to SARS-CoV-2 and its mutants in vaccination programs….
Array SPR has facilitated a paradigm shift in antibody screening, enabling higher information content assays to be conducted earlier in the research pipeline to streamline lead selection. This essentially combines…
…gD, we used multiple anti-gD MAbs from six antigenic communities and determined which ones interfered with this interaction. MAbs from three separate communities block gD-gH/gL binding and their epitopes encircle…