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…dendrogram and then the user gets to pick how many communities, what they would like to cluster their samples into. Combined Binary Dendrogram 0:15:12.8 DF: So shown here is the…

…therapeutics. Noah earned an MS from Pennsylvania State University developing chromatography-based fractionation techniques to isolate disease-specific serum biomarkers in Dengue infection and more recently an MBA from West Chester University…

…epitope specificity is an innate property that cannot be predicted. The epitope is highly complex and unknown a priori, and the in silico design of an equally complex complementary paratope…

…inject long enough or your kinetics are rapid enough that the interaction can come to an equilibrium where you see no real association or dissociation, then you are at a…

…left and PTM2 on the right, comprise this combination of PTMs. We call one proximal and one distal. What we did was generate recombinant antibody candidates to the combination of…

…of the particular binding domains in the community plots we have purple communities and a blue community indicated on the structure. So again, really early on with not a lot…

…cell, self-block. 0:20:18.8 TY: So if we zoom in on the lower portion of this heat map, looking at communities that we assigned as five and community 6 and community…

…and HTP experimentation to engineer biologics Abstract: This talk will cover our efforts to combine computational modeling, HTP protein-protein interaction assays, and biophysical characterization to engineering improved biologics. View the…

…sequences that comprise monoclonal IgE antibodies. Lastly, we re-engineer these IgE antibodies that cause allergic reactions and allergic individuals into IgG4 based therapeutics that can block the allergic cascade. We’ll…